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AQA | GCSE Biology | Paper 2 | 2025 Predictions

by Jen - Primrose Kitten on Mar 05, 2025

Hey 👋

Get ready to smash your AQA GCSE Biology Paper 2 with our 2025 Predicted Papers! 🧪📚

Last year, we nearly predicted EVERY single topic correctly! 🔥🎯 And this year, we’ve analysed all the trends and patterns again to bring you:

✅ Exam-style questions designed to match the real thing 📝
✅ Mark schemes so you know exactly how to score top marks ✅
✅ NEW for 2025 🎥 FREE video walkthroughs showing you how to write answers the way examiners love! 🏆

Want even MORE support? 🎯 Join our Masterclasses to get:
🌟 Access to our Revision Accelerator Course over the school holidays 🚀
🌟 Live exam prep sessions the night before your exam for that final confidence boost! 🎧📢

We’ve done the hard work, but don’t forget—revise everything to be fully prepared! 💡💪

Ready to boost your grade? Grab your predicted papers & masterclass spot

You’ve got this! 🌟💖

Which paper are you looking for?

  • AQA | GCSE Separate Science Biology | Higher | Pap …

  • AQA Trilogy | GCSE Combined Science Biology | High …

  • AQA | GCSE Separate Science Biology | Foundation | …

  • AQA Trilogy | GCSE Combined Science Biology | Foun …

AQA | GCSE Separate Science Biology | Higher | Paper 2 | 2025 Predicted Topics & Revision Guide

Here are our 2025 predictions for AQA GCSE Biology Higher Paper 2! 🔬✨ These are the topics we think are most likely to come up—so make sure you know them inside out! 💪📚


🧠 Structure and Function of the Nervous System

✅ Role of the CNS (central nervous system) – brain & spinal cord
✅ Reflex arcs – how they work and why they’re important
✅ The structure of a neurone and the role of synapses (neurotransmitters!)


🧠 The Brain

✅ Key structures – cerebrum, cerebellum, medulla, hypothalamus, pituitary gland
✅ How scientists study the brain – brain damage, electrical stimulation, MRI scans
✅ Why the brain is hard to treat (delicate, complex, not fully understood!)


🩸 Blood Glucose Control and Diabetes

✅ Role of insulin & glucagon in maintaining blood sugar levels
✅ Type 1 vs. Type 2 diabetes – causes, symptoms, and treatments
✅ Negative feedback and the role of the pancreas


🧬 Genetic Inheritance

✅ Alleles, dominant vs. recessive, genotypes & phenotypes
✅ Punnett squares – how to predict inheritance probabilities
✅ Genetic disorders – cystic fibrosis and polydactyly


🌱 Sampling Techniques (RP9 – Quadrats & Transects)

✅ Quadrats & transects – how and why we use them
✅ Random vs. systematic sampling – avoiding bias
✅ Abiotic & biotic factors affecting population size


🦠 Decay Practical (RP10)

✅ Factors affecting decay – temperature, oxygen, water, microbes
✅ Investigating milk decay – role of lipase & pH indicator
✅ Applications – composting & sewage treatment


🐶 Selective Breeding

✅ Process – choosing parents, breeding over generations
✅ Uses – crops (higher yield), animals (disease resistance, meat/milk production), pets (temperament, appearance)
✅ Risks – inbreeding, reduced genetic variation, increased health issues


🦎 Variation and Adaptation

✅ Genetic vs. environmental variation – examples of each
✅ Adaptations to environment – structural, behavioural, physiological
✅ How variation links to natural selection


🧬 Cloning

✅ Types of cloning – tissue culture, cuttings, embryo transplants, adult cell cloning
✅ Pros & cons – biodiversity loss, ethical issues, medical uses
✅ Applications – agriculture, conservation, medicine


🌳 Classification

✅ Carl Linnaeus’ classification system – kingdom, phylum, class, order, etc.
✅ Binomial naming system – Genus + species
✅ Three-domain system (Bacteria, Archaea, Eukarya)


🦴 Fossils and the Theory of Evolution

✅ What fossils are & how they form
✅ Evidence for evolution from fossil records
✅ Why some fossils are missing – decay, destruction, or never forming


🧬 Advantages and Disadvantages of Sexual and Asexual Reproduction

✅ Sexual reproduction – genetic variation, disease resistance, slower
✅ Asexual reproduction – clones, rapid reproduction, good for stable environments
✅ Examples – bacteria (binary fission), plants (runners, bulbs), fungi (spores)


🌍 Global Warming

✅ Causes – CO₂, methane, human activities
✅ Effects – rising sea levels, habitat loss, extreme weather
✅ Solutions – renewable energy, conservation, reducing carbon footprint


🍽️ Food Security

✅ Factors affecting food supply – population growth, climate change, farming practices
✅ Strategies – sustainable farming, reducing waste, GM crops (higher yield, pest resistance)


🦠 Uses of Biotechnology – Novel Food Production (Not GM!)

✅ Mycoprotein (Quorn!) – made using fungi (Fusarium), grown in fermenters
✅ Single-cell protein (SCP) – using bacteria & algae for protein-rich foods
✅ Enzymes in food production – lactase for lactose-free milk


🔥 Final Advice!

📌 These topics are predicted, but the exam could include anything from the syllabus—so revise everything!
📌 Practise past papers & mark schemes to get used to the question styles!
📌 Need extra help? Join our Masterclasses for revision sessions and live exam prep the night before! 🎧📢

You’ve got this! 💪✨

👉 Get your predicted papers & revision support here

AQA Trilogy | GCSE Combined Science Biology | Higher | Paper 2 | 2025 Predicted Topics & Revision Guide

Here are our 2025 predictions for AQA GCSE Combined Science Biology Higher Paper 2! 🔬✨ While we’ve carefully analysed trends, remember to revise everything to be fully prepared! 💡📚


⚡ Reflex Arc

✅ Automatic response – doesn’t involve the brain to keep reaction fast!
✅ Pathway: Stimulus → Receptor → Sensory neurone → Relay neurone → Motor neurone → Effector → Response
✅ Role of synapses – neurotransmitters pass the signal across gaps between neurones


🧬 Inheritance – Family Trees & Punnett Squares

✅ Dominant vs. recessive alleles – dominant only needs one copy to show
✅ How to use Punnett squares to predict genetic outcomes
✅ Family trees – spotting inherited traits & genetic disorders (e.g. polydactyly or cystic fibrosis)


🌱 Required Practical – Transect Sampling

✅ Quadrats & transects – used to measure how species are distributed in an area
✅ Abiotic factors (e.g. light, temperature, water) affect population sizes
✅ How to improve reliability: repeat, random sampling, control variables


🌿 Biotic and Abiotic Factors

✅ Biotic factors = living things affecting an ecosystem (e.g. predators, disease, food availability)
✅ Abiotic factors = non-living things affecting an ecosystem (e.g. temperature, pH, water levels)
✅ How changes in these factors affect population sizes and biodiversity


🌍 Global Warming

✅ Caused by greenhouse gases (carbon dioxide, methane) trapping heat
✅ Effects: rising sea levels, extreme weather, habitat destruction
✅ Solutions: renewable energy, reducing carbon footprint, planting trees


♻️ Waste Management

✅ Pollution types – land (landfills), water (plastics), air (smoke, acid rain)
✅ How human activity affects biodiversity (e.g. deforestation, habitat destruction)
✅ Ways to reduce waste – recycling, conservation, sustainable farming


🦋 Maintaining Biodiversity

✅ Why biodiversity is important – stable ecosystems, medicine, food chains
✅ How to conserve species – breeding programmes, habitat protection, reducing deforestation
✅ Role of governments & charities in conservation efforts


🐶 Selective Breeding

✅ Used to produce desirable traits (e.g. high-yield crops, disease-resistant animals)
✅ Risks – inbreeding (health problems), reduced variation, more disease susceptibility
✅ Ethical concerns – animal welfare, reduced gene pool


🦴 Classification, Fossils, and Evolution

✅ Classification – Linnaeus’ system (Kingdom, Phylum, Class…) & three-domain system (Bacteria, Archaea, Eukarya)
✅ Fossils – evidence for evolution, how they form, why some are missing
✅ Natural selection – survival of the fittest, how species evolve over time


🩸 Contraception and Menstrual Cycle Hormones

✅ Key hormones:

  • FSH – matures the egg

  • LH – releases the egg (ovulation)

  • Oestrogen & progesterone – control the cycle & maintain uterus lining
    ✅ Contraception types:

  • Hormonal (pill, implant, injection) – stop ovulation

  • Barrier (condoms, diaphragms) – prevent sperm reaching egg

  • Surgical (sterilisation) – permanent prevention


💡 Final Advice & Masterclasses!

🔥 These topics are predicted, but anything from the syllabus could appear—so revise widely!
🔥 Practice past papers and learn mark schemes to see how examiners award points!
🔥 Join our Masterclasses for extra support, revision boosters, and live exam prep sessions the night before! 🎧📢

💙 Most importantly, take care of yourself! Exam stress is real, but your grades do not define you! Take breaks, sleep well, and believe in yourself—you’ve got this! 💪✨

👉 Get your predicted papers & masterclass spot here

AQA | GCSE Separate Science Biology | Foundation | Paper 2 | 2025 Predicted Topics & Revision Guide

Here are our 2025 predictions for AQA GCSE Biology Foundation Paper 2! 🔬✨ These are key topics we think might come up, so make sure you’re confident with them! But remember—revise everything just in case! 💪📚


⚡ Reflex Arc

✅ A fast, automatic response to protect the body
✅ Pathway: Stimulus → Receptor → Sensory neurone → Relay neurone → Motor neurone → Effector → Response
✅ Reflexes help to avoid injury (e.g. pulling hand away from something hot)


🧠 The Brain

✅ Controls movement, memory, emotions, and bodily functions
✅ Key parts to know:

  • Cerebrum – thinking, memory, speech

  • Cerebellum – balance and coordination

  • Medulla – controls heartbeat and breathing
    ✅ Why brain damage is difficult to treat – delicate & complex!


🩸 Blood Glucose Control and Diabetes

✅ The pancreas controls blood sugar levels using two hormones:

  • Insulin – lowers blood sugar when it’s too high

  • Glucagon – raises blood sugar when it’s too low
    ✅ Diabetes:

  • Type 1 – body doesn’t produce insulin (needs injections)

  • Type 2 – linked to diet and lifestyle (managed with healthy eating & exercise)


🚽 Excretion

✅ The removal of waste products from the body
✅ The kidneys filter blood to remove urea, water, and salts (forming urine)
✅ The lungs remove carbon dioxide, and the skin removes sweat


🧬 Inheritance – Family Trees & Punnett Squares

✅ Dominant vs. recessive genes – dominant only needs one copy to show
✅ How to use a Punnett square to predict genetic traits
✅ Family trees help show how traits are passed through generations


🌱 Required Practical – Transect Sampling

✅ Quadrats & transects – used to measure plant and animal distribution
✅ Abiotic factors (e.g. light, temperature) affect where organisms live
✅ To make results reliable – repeat tests and take averages


🌿 Biotic and Abiotic Factors

✅ Biotic (living) factors: predators, food availability, disease
✅ Abiotic (non-living) factors: temperature, water, light, soil type
✅ Changes in these factors can increase or decrease population sizes


🌍 Global Warming

✅ Causes: too much carbon dioxide (CO₂) & methane in the atmosphere
✅ Effects: rising temperatures, melting ice, extreme weather
✅ Ways to reduce it: using less fossil fuels, planting more trees


🍽️ Food Security

✅ Challenges: growing population, climate change, overfishing
✅ Solutions:

  • Sustainable farming methods

  • Reducing food waste

  • Improving food transport & storage


🦠 Biotechnology

✅ Using microorganisms to help in food and medicine production
✅ Examples:

  • Mycoprotein (Quorn!) – made using fungi

  • Bacteria used to produce insulin for diabetes treatment


🐶 Selective Breeding

✅ Choosing parents with desired traits to breed together
✅ Used for:

  • Farming (cows that produce more milk)

  • Pets (dogs with good temperaments)

  • Crops (disease-resistant plants)
    ✅ Risks – inbreeding can cause health problems


🦴 Classification, Fossils, and Evolution

✅ Classification – grouping organisms based on similarities
✅ Fossils – evidence for evolution, show how species have changed over time
✅ Evolution – species gradually change to adapt to their environment


🧬 Theory of Evolution

✅ Charles Darwin’s theory – natural selection (survival of the fittest)
✅ Mutations cause variation, and beneficial traits get passed on
✅ Over time, this leads to new species forming


🧪 Cloning

✅ Types of cloning:

  • Cuttings & tissue culture (for plants)

  • Embryo transplants (for animals)

  • Adult cell cloning (e.g. Dolly the sheep)
    ✅ Benefits – conservation & farming
    ✅ Risks – ethical concerns, lack of genetic variation


🧬 Sexual and Asexual Reproduction

✅ Sexual reproduction – two parents, produces variation (important for evolution!)
✅ Asexual reproduction – one parent, identical offspring (good for quick reproduction)
✅ Examples:

  • Bacteria & fungi reproduce asexually

  • Plants can do both (e.g. runners in strawberries)


💡 Final Advice & Masterclasses!

🔥 These topics are predicted, but remember—revise everything!
🔥 Practise past papers to get used to the types of questions that come up
🔥 Need extra support? Join our Masterclasses! We’ve got revision boosters and live exam prep the night before to help you feel ready! 🎧📢

💙 Most importantly, look after yourself! Exam stress is normal, but your grades do not define your worth. Take breaks, eat well, and believe in yourself—you’ve got this! 💪✨

👉 Get your predicted papers & masterclass spot here

AQA Trilogy | GCSE Combined Science Biology | Foundation | Paper 2 | 2025 Predicted Topics & Revision Guide

Here are our 2025 predictions for AQA GCSE Combined Science Biology Foundation Paper 2! 🔬✨ These are key topics we think might come up, so make sure you’re confident with them! But remember—revise everything to be fully prepared! 💪📚


⚡ Reflex Arc

✅ A fast, automatic response to protect the body from harm
✅ Pathway: Stimulus → Receptor → Sensory neurone → Relay neurone → Motor neurone → Effector → Response
✅ Example: Pulling your hand away from something hot


🧬 Inheritance – Family Trees & Punnett Squares

✅ Genes are passed from parents to offspring
✅ Dominant vs. recessive traits – dominant only needs one copy to show
✅ How to use Punnett squares to predict how traits are inherited
✅ Family trees show how genetic conditions are passed down


🌱 Required Practical – Transect Sampling

✅ Quadrats & transects help measure how plants & animals are spread in an area
✅ Abiotic factors (e.g. temperature, light) affect where organisms live
✅ To improve accuracy – repeat tests and take averages


🌿 Biotic and Abiotic Factors

✅ Biotic factors (living things) – predators, food supply, disease
✅ Abiotic factors (non-living) – temperature, water, soil pH, light
✅ Changes in these factors can affect population sizes


🌍 Global Warming

✅ Causes: Too much carbon dioxide & methane from cars, factories, farming
✅ Effects: Rising sea levels, extreme weather, habitat destruction
✅ Ways to reduce it: Renewable energy, recycling, planting trees


♻️ Waste Management

✅ Types of pollution:

  • Land (litter, landfills)

  • Water (plastic in oceans)

  • Air (fumes, smoke, acid rain)
    ✅ Solutions: Recycling, reducing plastic use, better waste disposal


🦋 Maintaining Biodiversity

✅ Why it’s important: Keeps ecosystems stable, provides food & medicine
✅ Threats to biodiversity: Deforestation, climate change, pollution
✅ How to protect it: Nature reserves, reforestation, reducing waste


🐶 Selective Breeding

✅ Humans choose parents with desirable traits (e.g. faster-growing crops, high milk-yield cows)
✅ Used for: Farming, pets, disease-resistant plants
✅ Risks – inbreeding can cause health problems


🦴 Classification, Fossils, and Evolution

✅ Classification: Grouping organisms based on similarities (e.g. mammals, reptiles)
✅ Fossils: Show evidence of how species have changed over time
✅ Evolution: Natural selection – survival of the fittest leads to gradual changes in species


🩸 Contraception and Menstrual Cycle Hormones

✅ Key hormones:

  • FSH – matures the egg

  • LH – releases the egg (ovulation)

  • Oestrogen & progesterone – control the cycle & maintain uterus lining
    ✅ Contraception methods:

  • Hormonal (pill, implant, injection) – stops ovulation

  • Barrier (condoms, diaphragms) – stops sperm reaching the egg

  • Surgical (sterilisation) – permanent prevention


💡 Final Advice & Masterclasses!

🔥 These topics are predicted, but remember—revise everything!
🔥 Practise past papers to get used to the types of questions that come up!
🔥 Need extra support? Join our Masterclasses! We’ve got revision boosters and live exam prep sessions the night before to help you feel exam-ready! 🎧📢

💙 Most importantly, look after yourself! Exam stress is real, but your grades do not define your worth. Take breaks, eat well, and believe in yourself—you’ve got this! 💪✨

👉 Get your predicted papers & masterclass spot here



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AQA GCSE Biology Paper 1 | Free Revision Course
Hetal P. (Aylesbury, GB)

I’ve started using biology paper 1 course for my year 9 son as the school has started some of the gcse content already. We will go on to buy the full version in year 10. The notes and quizzes are very good. Some pictures/diagrammes alongside the notes will really help.

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A-Level Chemistry | Revision plan
Prasad (Barnet, GB)

A-Level Chemistry | Revision plan

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A-Level Environmental Science | Free Revision Guide
Lilian G. (Leyton, GB)
Nice resorce

Found it very usefull

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GCSE Science Predicted Papers | OCR Gateway
kathy z. (Brent, GB)
Katy

They great videos really helpful and informative

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GCSE Science revision plans
Zaid G. (Lambeth, GB)

GCSE Science revision plans

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